about FPL

Who has FPL? Please send me pics.

Familial Partial Lipodystrophy

 

Familial partial lipodystrophy (FPL) is a rare genetic disorder characterized by selective, progressive loss of body fat (adipose tissue) from various areas of the body. Often, there is reduced subcutaneous fat in the arms and legs while fat deposits increase in the neck, face and intra-abdominal regions. Other complications include diabetes, elevated triglycerides, and an inability to breakdown glucose in the body. Symptoms are generally first noticed during puberty. Six different subtypes of FPL have been identified as different genetic mutations. Prevalence of all types of FPL is thought to be at about 1 in every 1,000,000 births worldwide, with a higher rate of female births.

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